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Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing antibody.
Seidel F, Fluiter K, Kleemann R, Worms N, van Nieuwkoop A, Caspers MPM, Grigoriadis N, Kiliaan AJ, Baas F, Michailidou I, Morrison MC. Seidel F, et al. Among authors: van nieuwkoop a. Front Cell Neurosci. 2023 Jun 29;17:1205261. doi: 10.3389/fncel.2023.1205261. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37457817 Free PMC article.
Diet and exercise reduce pre-existing NASH and fibrosis and have additional beneficial effects on the vasculature, adipose tissue and skeletal muscle via organ-crosstalk.
van den Hoek AM, de Jong JCBC, Worms N, van Nieuwkoop A, Voskuilen M, Menke AL, Lek S, Caspers MPM, Verschuren L, Kleemann R. van den Hoek AM, et al. Among authors: van nieuwkoop a. Metabolism. 2021 Nov;124:154873. doi: 10.1016/j.metabol.2021.154873. Epub 2021 Sep 1. Metabolism. 2021. PMID: 34478753 Free article.
Corrigendum: Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing antibody.
Seidel F, Fluiter K, Kleemann R, Worms N, van Nieuwkoop A, Caspers MPM, Grigoriadis N, Kiliaan AJ, Baas F, Michailidou I, Morrison MC. Seidel F, et al. Among authors: van nieuwkoop a. Front Cell Neurosci. 2023 Aug 8;17:1267913. doi: 10.3389/fncel.2023.1267913. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37614912 Free PMC article.
Local Cre-mediated gene recombination in vascular smooth muscle cells in mice.
Zadelaar SM, Boesten LS, Pires NM, van Nieuwkoop A, Biessen EA, Jukema W, Havekes LM, van Vlijmen BJ, Willems van Dijk K. Zadelaar SM, et al. Among authors: van nieuwkoop a. Transgenic Res. 2006 Feb;15(1):31-6. doi: 10.1007/s11248-005-3226-z. Transgenic Res. 2006. PMID: 16475008